The Nelson Mandela Institution for Knowledge Building and the Advancement of Science and Technology in Sub-Saharan Africa (NMI) is a private and independent organization established to provide the leadership needed to address the growing knowledge gap between Sub-Saharan Africa (SSA) and the rest of the world. It will play both a direct and catalytic role in improving learning and the application of science and technology to the development needs of SSA. To achieve its objectives, the NMI is establishing the African Institute of Science and Technology (AIST). AIST will be a world-class learning, teaching, and research institution and will produce young entrepreneurs and leaders committed to creating and adapting knowledge to transform local communities and improve the human condition across the African continent. NMI will also develop the Sub-Saharan African Learning Network (SSALN) to promote continuing education and learning across the continent.